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Reading & Research

  • American Heart Association. 2002 Heart and Stroke Statistical Up-date. Dallas, TX: American Heart Association, 2001.

  • Kim MC, Kini A, Sharma SK. Refractory angina pectoris: mechanism and therapeutic options. J Am Coll Cardiol 2002;39:923–34.

  • Stys T, Lawson WE, Hui JCK, Lang G, Liuzzo J, Cohn PF. Acute hemodynamic effects and angina improvement with enhanced external counterpulsation. Angiology 2001;52:653–8.

  • Zheng ZS, Li TM, Kambic H, et al. Sequential external counterpulsation (SECP) in China. Trans Am Soc Artif Intern Organs 1983; 29:599 –603.

  • Lawson WE, Hui JCK, Soroff HS, et al. Efficacy of enhanced external counterpulsation in the treatment of angina pectoris. Am J Cardiol 1992;70:859 –62.

  • Lawson WE, Hui JCK, Zheng ZS, et al. Can angiographic findings predict which coronary patients will benefit from enhanced external counterpulsation? Am J Cardiol 1996;77:1107–9.

  • Lawson WE, Hui JCK, Guo T, Burger L, Cohn PF. Prior revascularization increases the effectiveness of enhanced external counterpulsation. Clin Cardiol 1998;21:841–4.

  • Lawson WE, Hui JCK, Cohn PF. Long-term prognosis of patients with angina treated with enhanced external counterpulsation: five-year follow-up study. Clin Cardiol 2000;23:254 –8.

  • Stys TP, Lawson WE, Hui JCK, et al. Effects of enhanced external counterpulsation on stress radionuclide coronary perfusion and exercise capacity in chronic stable angina pectoris. Am J Cardiol 2002;89:822–4.

  • Masuda D, Nohara R, Hirai T, et al. Enhanced external counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina. Eur Heart J 2001;22:1451–8.

  • Lawson WE, Hui JCK, Zheng ZS, et al. Improved exercise tolerance following enhanced external counterpulsation: cardiac or peripheral effect? Cardiology 1996;87:271–5.

  • Urano H, Ikeda H, Ueno T, Matsumoto T, Murohara T, Imaizumi T. Enhanced external counterpulsation improves exercise tolerance, reduces exercise-induced myocardial ischemia and improves left ventricular diastolic filling in patients with coronary artery disease. J Am Coll Cardiol 2001;37:93–9.

  • Fricchione GL, Jaghab K, Lawson W, et al. Psychosocial effects of enhanced external counterpulsation in the angina patient. Psychoso-matics 1995;36:494 –7.

  • Springer S, Fife A, Lawson W, et al. Psychosocial effects of enhanced external counterpulsation in the angina patient: a second study. Psychosomatics 2001;42:124 –32.

  • Arora RR, Chou TM, Jain D, et al. The Multicenter Study of Enhanced External Counterpulsation (MUST-EECP): effect of EECP on exercise-induced myocardial ischemia and anginal episodes. J Am Coll Cardiol 1999;33:1833–40.

  • Arora RR, Chou TM, Jain D, et al. Effects of enhanced external counterpulsation on health-related quality of life continue 12 months after treatment: a substudy of the multicenter study of enhanced external counterpulsation. J Investig Med 2002;50:25–32.

  • Barsness G, Feldman AM, Holmes DR Jr., Holubkov R, Kelsey SF, Kennard ED, and the International EECP Patient Registry Investigators. The International EECP Patient Registry (IEPR): design, methods, baseline characteristics, and acute results. Clin Cardiol 2001;24:435–42.

  • Lawson WE, Hui JCK, Lang G. Treatment benefit in the enhanced external counterpulsation consortium. Cardiology 2000;94:31–5.

  • Lawson WE, Hui JCK, Zheng ZS, et al. Three-year sustained benefit from enhanced external counterpulsation in chronic angina pectoris. Am J Cardiol 1995;75:840 –1.

  • Michaels AD, Accad M, Ports TA, Grossman W. Left ventricular systolic unloading and augmentation of intracoronary pressure and Doppler flow during enhanced external counterpulsation. Circulation 2002;106:1237–42.

  • Barsness GW. Enhanced external counterpulsation in unrevascularizable patients. Curr Interv Cardiol Rep 2001;3:37–43.

  • Werner D, Schneider M, Weise M, Nonnast-Daniel B, Daniel WG. Pneumatic external counterpulsation: a new noninvasive method to improve organ perfusion. Am J Cardiol 1999;84:950 –2.

  • Suresh K, Simandl S, Lawson WE, et al. Maximizing the hemodynamic benefit of enhanced external counterpulsation. Clin Cardiol 1998;21:649 –53.

  • Michaels AD, Kennard ED, Kelsey SF, et al. Does higher diastolic augmentation predict clinical benefit from enhanced external counter-pulsation? Data from the International EECP Patient Registry (IEPR). Clin Cardiol 2001;24:453–8.

  • Lakshmi MV, Kennard ED, Kelsey SF, Holubkov R, Michaels AD. Relation of the pattern of diastolic augmentation during a course of enhanced external counterpulsation (EECP) to clinical benefit (from the International EECP Patient Registry [IEPR]). Am J Cardiol 2002;89:1303–5.

  • Celermajer DS. Endothelial dysfunction: does it matter? Is it reversible? J Am Coll Cardiol 1997;30:325–33.

  • Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801–9.

  • Bonetti PO, Lerman LO, Lerman A. Endothelial dysfunction: a marker of atherosclerotic risk. Arterioscler Thromb Vasc Biol 2003;23:168 –75.

  • Lerman A, Burnett JC Jr. Intact and altered endothelium in regulation of vasomotion. Circulation 1992;86 Suppl III:12–9.

  • Kern MJ, Aguirre FV, Tatineni S, et al. Enhanced coronary blood flow velocity during intraaortic balloon counterpulsation in critically ill patients. J Am Coll Cardiol 1993;21:359 –68.

  • Kern MJ, Aguirre F, Bach R, Donohue T, Siegel R, Segal J. Augmentation of coronary blood flow by intra-aortic balloon pumping in patients after coronary angioplasty. Circulation 1993;87:500 –11.

  • Corson MA, James NL, Latta SE, Nerem RM, Berk BC, Harrison DG. Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress. Circ Res 1996;79:984 –91.

  • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 1999;399:601–5.

  • Davies PF. Flow-mediated endothelial mechanotransduction. Physiol Rev 1995;75:519 –60.

  • Kuchan MJ, Frangos JA. Shear stress regulates endothelin-1 release via protein kinase C and cGMP in cultured endothelial cells. Am J Physiol 1993;264:H150–6.

  • Niebauer J, Cooke JP. Cardiovascular effects of exercise: role of endothelial shear stress. J Am Coll Cardiol 1996;28:1652–60.

  • Traub O, Berk BC. Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arterioscler Thromb Vasc Biol 1998;18:677–85.

  • Masuda D, Nohara R, Hirai T, et al. Enhanced external counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina. Eur Heart J 2001;22:1451–8.

  • Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 2000;87:840 –4.

  • Lawson WE, Hui JCK, Lu L, Zheng ZS, Zhang MQ. Beneficial effects of EECP on the reninangiotension system in patients with coronary artery disease (abstr). Eur Heart J 2001;22 Suppl:538.

  • Mollnau H, Wendt M, Szo¨ cs K, et al. Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circ Res 2002;90:e58 – 65.

  • Wilkinson IB, Qasem A, McEniery CM, Webb DJ, Avolino AP, Cockcroft JR. Nitric oxide regulates local arterial distensibility in vivo. Circulation 2002;105:213–7.

  • Kersten JR, Pagel PS, Chilian WM, Warltier DC. Multifactorial basis for coronary collateralization: a complex adaptive response to ischemia. Cardiovasc Res 1999;43:44 –57.

  • Cai D, Wu R, Shao Y. Experimental study of the effect of external counterpulsation on blood circulation in the lower extremities. Clin Invest Med 2000;23:239 –47.

  • Van Royen N, Piek JJ, Buschmann I, et al. Stimulation of arteriogenesis; a new concept for the treatment of arterial occlusive disease. Cardiovasc Res 2001;49:543–53.

  • Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, Holash J. Vascular-specific growth factors and blood vessel formation. Nature 2000;407:242–8.

  • Gan L, Miocic M, Doroudi R, Selin-Sjögren L, Jern S. Distinct regulation of vascular endothelial growth factor in intact human conduit vessels exposed to laminar fluid shear stress and pressure. Biochem Biophys Res Commun 2000;272:490 –6.

  • Resnick N, Collins T, Atkinson W, Bonthron DT Dewey CF Jr., Gimbrone MA. Platelet-derived growth factor B chain promoter contains a cis-acting shear-stress-responsive element. Proc Natl Acad Sci USA 1993;90:4591–5.

  • Masuda D, Nohara K, Kataoka K, Hosokawa R, Kanbara N, Fujita M. Enhanced external counterpulsation promotes angiogenesis factors in patients with chronic stable angina (abstr). Circulation 2001;104: II445.

  • Van Belle E, Witzenbichler B, Chen D, et al. Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor. Circulation 1998;97:381–90.

  • Ziche M, Morbidelli L. Nitric oxide and angiogenesis. J Neurooncol 2000;50:139 –48.

  • Hood JD, Meininger CJ, Ziche M, Granger HJ. VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells. Am J Physiol 1998;274:H1054–8.

  • Papapetropoulos A, García Cardeña G, Madri JA, Sessa WC. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest 1997;100:3131–9.

  • Fulton D, Gratton JP, McCabe TJ, et al. Regulation of endothelium-derived nitric oxide production by the protein kinase. Akt Nature 1999;399:597–601.

  • Ku DD, Zaleski JK, Liu S, Brock TA. Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries. Am J Physiol 1993;265:H586–92.

  • Murohara T, Asahara T, Silver M, et al. Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest 1998;101:2567–78.

  • Freedman SB, Isner JM. Therapeutic angiogenesis for coronary artery disease. Ann Intern Med 2002;136:54 –71.

  • Takahashi T, Kalka C, Masuda H, et al. Ischemia- and cytokine-induced mobilization of bonemarrow-derived endothelial progenitor cells for neovascularization. Nat Med 1999;5:434 –8.

  • Asahara T, Takahashi T, Masuda H, et al. VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 1999;18:3964 –72.

  • Kalka C, Masuda H, Takahashi T, et al. Vascular endothelial growth factor165 gene transfer augments circulating endothelial progenitor cells in human subjects. Circ Res 2000;86:1198 –202.

  • Cohen LS, Mullins CB, Mitchell JH, Alsobrook HD. Sequenced external counterpulsation and intraaortic balloon pumping in cardiogenic shock. Am J Cardiol 1973;32:656 –61.

  • Singh M Holmes DR Jr., Tajik AJ, Barsness GW. Noninvasive revascularization by enhanced external counterpulsation: a case study and literature review. Mayo Clin Proc 2000;75:961–5.

  • Gorcsan J III, Crawford L, Soran O, et al. Improvement in left ventricular performance by enhanced external counterpulsation in patients with heart failure. J Am Coll Cardiol 2000;35 Suppl:230A.

  • Soran OZ, Fleishman B, DeMarco T, et al. Enhanced external counterpulsation in patients with heart failure: a multicenter feasibility study. Congest Heart Fail 2002;8:204 –8.

  • Soran O, Kennard ED, Holubkov R, Strobeck J, Feldman AM. Six month outcome of patients with left ventricular dysfunction treated with enhanced external counterpulsation for chronic angina. Eur Heart J 2000;21 Suppl:598.

  • Kaptchuk TJ, Goldman P, Stone DA, Stason WB. Do medical devices have enhanced placebo effects? J Clin Epidemiol 2000;53:786 –92.

 
   
 
     


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